{"id":4173,"date":"2022-09-20T17:29:25","date_gmt":"2022-09-20T15:29:25","guid":{"rendered":"http:\/\/www.sfbmec.fr\/?p=4173"},"modified":"2022-09-20T17:29:25","modified_gmt":"2022-09-20T15:29:25","slug":"poste-dater-en-physiologie-a-la-faculte-de-pharmacie-de-limoges","status":"publish","type":"post","link":"http:\/\/www.sfbmec.fr\/?p=4173","title":{"rendered":"Poste d’ATER en physiologie \u00e0 la Facult\u00e9 de Pharmacie de Limoges"},"content":{"rendered":"

Date limite de candidature :<\/strong> 23 septembre 2022<\/p>\n

Fiche de poste disponible ICI<\/a><\/strong><\/p>\n

Profil enseignement :<\/strong><\/p>\n

L\u2019ATER devra r\u00e9aliser des en<\/span>seignements de physiologie<\/span> (Pharmacie)<\/span> :<\/span><\/span>
–<\/span> en 2<\/span>\u00e8me<\/span> ann\u00e9e (<\/span>notamment,<\/span> introduction g\u00e9n\u00e9rale \u00e0 la physiologie, physiologie r\u00e9nale,<\/span>
respiratoire et du syst\u00e8me nerveux),<\/span><\/span>
–<\/span> en<\/span> 3<\/span>\u00e8me<\/span> ann\u00e9e (<\/span>notamment,<\/span> neurophysiologie, douleur)<\/span> et<\/span><\/span>
–<\/span> en<\/span> 4<\/span>\u00e8me<\/span> ann\u00e9e<\/span> (<\/span>notamment,<\/span> phy<\/span>siologie respiratoire et r\u00e9nale).<\/span><\/span><\/p>\n

Des TDs (physiologie respiratoire, \u00e9lectrocardiogramme, conduction nerveuse) utilisant <\/span>du<\/span> mat\u00e9riel<\/span> et<\/span> des<\/span> logiciels<\/span> d\u00e9velopp\u00e9s<\/span> par<\/span> l\u2019entreprise<\/span> ADInstruments<\/span> (avec<\/span> un <\/span>apprentissage actif des \u00e9tudiants<\/span> exploitant<\/span> une techno<\/span>logie \u00e9volutive bas\u00e9e sur le cloud<\/span>) <\/span>seront r\u00e9alis\u00e9s.<\/span><\/span>
Il interviendra \u00e9galement<\/span> en<\/span> Licences Acc\u00e8s Sant\u00e9<\/span> (<\/span>LAS<\/span>)<\/span> 1<\/span>\u00e8re<\/span> et 2<\/span>\u00e8me<\/span> ann\u00e9e<\/span>.<\/span> Ces <\/span>enseignements<\/span> concerneront<\/span> l\u2019ensemble<\/span> de<\/span> la<\/span> physiologie<\/span>.<\/span> Des<\/span> aspects<\/span> de <\/span>physiopathologie seront<\/span> \u00e9galement a<\/span>bord\u00e9s. <\/span><\/span>Des cour<\/span>s<\/span> de Physiologie sp\u00e9cifiques pour les \u00e9tudiants de Pharmacie qui pr\u00e9parent <\/span>l\u2019internat<\/span> sont<\/span> \u00e9galement<\/span> dispens\u00e9s<\/span>.<\/span> Il<\/span> interviendra<\/span> dans<\/span> le<\/span> DU<\/span> \u00ab<\/span> P<\/span>harmacien <\/span>orthop\u00e9diste<\/span> \u2013<\/span> orth\u00e9siste<\/span> \u00bb.<\/span><\/span><\/p>\n

Profil recherche :<\/strong><\/p>\n

L\u2019ATER<\/span> devra<\/span> notamment<\/span> s\u2019impliquer<\/span> dans<\/span> un<\/span> projet<\/span> (Na<\/span>noCur)<\/span> soutenu<\/span> par <\/span>l\u2019<\/span>Association<\/span> F<\/span>ran\u00e7aise contre les<\/span> M<\/span>yopathies<\/span> (<\/span>AFM<\/span>–<\/span>T\u00e9l\u00e9thon)<\/span>.<\/span> Ce projet concerne la <\/span>curcumine qui a montr\u00e9 des effets b\u00e9n\u00e9fiques dans di<\/span>ff\u00e9rents<\/span> mod\u00e8les de neuropathies <\/span>p\u00e9riph\u00e9riques.<\/span> Cependant<\/span>, la curcumine a un mauvais profil pharmacoc<\/span>in\u00e9tique, ce qui <\/span>limite consid\u00e9rablement son utilisation th\u00e9rapeutique. R\u00e9cemment, nous avons montr\u00e9 <\/span>que<\/span> l’administration<\/span> de<\/span> curcumine<\/span> li\u00e9e<\/span> \u00e0<\/span> un<\/span> vecteur<\/span> nanoparticulaire<\/span> am\u00e9liore <\/span>consid\u00e9rablement<\/span> sa biodisponibilit\u00e9 et<\/span> r\u00e9duit significativement les d\u00e9ficits<\/span> observ\u00e9s <\/span>chez<\/span> de<\/span>s<\/span> rats transg\u00e9niques reproduisant la physiopathologie de la maladie de Charcot<\/span>– <\/span>Marie<\/span>–<\/span>Tooth de type 1A (CMT1A), principale neuropathie p\u00e9riph\u00e9rique h\u00e9r\u00e9ditaire. <\/span>L’objectif de ce projet de recherche est de confirmer l’efficacit\u00e9 de cette for<\/span>mulation <\/span>nanoparticulaire de curcumine dans le traitement de la maladie CMT1A<\/span> et de montrer <\/span>son int\u00e9r\u00eat dans d\u2019autres types de neuropathie p\u00e9riph\u00e9rique<\/span>.<\/span><\/span><\/p>\n

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