Présidente (bureau)

ROUSSELLE Patricia

Cell / microenvironment cross-talk and tissue repair lab
Biologie Tissulaire et Ingénierie Thérapeutique Department
UMR 5305 – CNRS/UCB Lyon 1- SFR BioSciences Gerland-Lyon Sud
7 passage du Vercors – 69367 Lyon Cedex 07, France
Phone: 33 (0)4 72 72 26 39 | | Fax: 33 (0)4 72 72 26 02
Email address : patricia.rousselle@ibcp.fr
Website: http://www.ibcp.fr/lbti/-Environnement-Matriciel-Reparation-

Parcours professionnel

Patricia Rousselle is research director at CNRS in France where she leads a lab in the Tissue Biology and Therapeutic Engineering Department of the Institute of Protein Biology and Chemistry in Lyon. This department is one of the major centres in France specialising in the extracellular matrix and tissue repair field of research. Developing both biochemical and cell biology approaches, her group is interested in analysing the behaviour of keratinocytes during the reepithelialisation phase of wound repair and their interaction with extracellular matrix components. Besides, she develops translational research through collaborations with clinicians of the Lyon Burn Centre and industrial partners. Patricia is the present president of the French Matrix Society and is also a board member of the European Tissue Repair Society. Patricia obtained a doctorate in Pharmacy in 1988 and pursued a four-year residency in clinical biology at Lyon Hospitals, where she also gained an MSc in Molecular and Cellular Biology in 1990. Being interested in adhesion mechanisms of the epidermis, she started a PhD program with Prof Bob Burgeson at the Shriners Hospital For Crippled Children in Portland, USA, where she discovered the important dermal epidermal junction protein laminin 332. She thereafter joined the Cutaneous Biology Research Center in Boston, USA, to work on basement membrane biology, before she joined CNRS to set up her own group in 1995. Patricia Rousselle has published more than 90 articles on extracellular matrix proteins with a focus on laminins and proteoglycans, in internationally renowned journals. Dr. Rousselle’s special research interests include the role of basement membrane components and cell receptors, such as syndecans, in epithelial homeostasis and repair.


Secrétaire général (bureau)

EMONARD Hervé

UMR CNRS/URCA 7369 MEDyC
Responsable de l’équipe « Protéolyse et Cancer » – Laboratoire « Signalisation et Récepteurs Matriciels »
UFR Sciences Exactes et Naturelles – Bât. 18 RDC, bureau BR 21
Campus du Moulin de la Housse, BP 1039 – Chemin des Rouliers – 51687 REIMS Cedex 2
Tel: +33 (0)3 26 91 83 61 – Fax: +33 (0)3 26 91 83 66
Email address: herve.emonard@univ-reims.fr

Parcours professionnel

Hervé Emonard is associate scientist at CNRS in France where he leads the Proteolysis and Cancer Team of the UMR 7369 CNRS/URCA in Reims. Our unit is the leader in France for investigating the cytokine-like effects of degradation products, the matrikines, from two major components of the extracellular matrix, collagen and elastin. These matrikines are essentially studied in tumoral and vascular pathologies. Hervé is the present secretary of the French Extracellular Matrix Society.
Hervé obtained his PhD in 1984 at Lyon. A two-year post-doctoral fellowship in the laboratory of Profs Charles M. Lapière and Jean-Michel Foidart (University of Liege, Belgium) allowed him to familiarize himself with a family of proteolytic enzymes degrading extracellular matrix, the matrix metalloproteinases, MMPs. He joined CNRS in 1986 to study the extracellular matrix breakdown during hepatic fibrosis in Lyon. Then he moved to Reims in 1995, in the CNRS unit of Prof. François-Xavier Maquart to set up a group studying mechanisms of MMP inhibition with Prof. William Hornebeck. Hervé developped a strong collaboration with Prof. Pierre J. Courtoy (de Duve Institute, UCL, Brussels, Belgium) to understand the regulation of MMP extracellular levels by LRP-1-mediated endocytosis. Hervé Emonard has published more than 70 articles on the regulation of MMP activities, with a focus on MMP-2 and LRP-1.


Trésoriere (bureau)

THERET Nathalie

Dynamique du Microenvironnement et Cancer
IRSET, Institut de Recherche en Santé, Environnement et Travail
INSERM U1085
2 avenue du Professeur Léon Bernard – 35043 Rennes Cédex
Tel: +33 (0)223 23 48 11
Email address: nathalie.theret@univ‐rennes1.fr

Parcours professionnel

Nathalie Théret is research Director at INSERM in France where she heads a research team at the Research Institute in Health, Environment and work (IRSET) supported by INSERM and University of Rennes 1. IRSET’s mission is to study biological processes and environmental factors that influence human health. Using multi-scale approaches combining molecular and cellular biology, biophysical and computational methods, her group is interested in studying extracellular matrix (ECM) remodeling in chronic liver diseases. Studies focus on the role of disintegrins and metalloproteases (ADAM) on TGF‐β signaling, the effects of ECM stiffness on hepatocyte functionality and the identification of a structure‐based signature for liver fibrosis evaluation by multiphotonic microscopy. Nathalie is the present treasury of the French Extracellular Matrix Society. Nathalie obtained her PhD in Pharmaceutic sciences in 1988 and pursued a two‐year post‐doctoral position in the laboratory of Pr Fruchart at Pasteur Institute (Lille) where she studied reverse cholesterol transport in cardiovascular diseases. She joined INSERM in 1991 and managed the «BioAvenir» Research Program in collaboration with Rhone Poulenc Roher Corporation focusing on the role of AI and AIV apolipoproteins. Next she moved in 1993 to the INSERM Unit directed by Pr Guillouzo (University of Rennes) and joined Dr B.Clement’s team to develop studies on extracellular matrix remodeling in liver cancers. To address the biological complexity of liver fibrosis and tumor progression, she sets up her own group in 2007 and develops systemic approaches for high-throughput data analysis and molecular modeling in collaboration with the Research Institute in Computational Research (INRIA). Nathalie Théret has published more than 70 articles and her research interests include ADAM proteins, TGFβ signaling and fibrosis.


Conseiller

CARREIRAS Franck

Université de Cergy Pontoise, ERRMECe, EA1391, Groupe MEC-uP
UFR Science et Technique
2 Av. Adolphe Chauvin
95302 CERGY-PONTOISE Cedex
Phone: +33 (0)1 34 25 66 75 | | Fax: +33 (0)1 34 25 66 94
Email address: franck.carreiras@u-cergy.fr

Parcours professionnel


Conseiller

DEMOOR Magali

Laboratoire Microenvironnement Cellulaire et Pathologies (MILPAT), EA 4652
Faculté de Médecine Côte de Nacre, Université de CAEN Basse Normandie
14032 CAEN Cedex
Phone: +33 (0)2 31 06 82 18
Email address: magali.demoor@unicaen.fr

Parcours professionnel


Conseiller

DUCA Laurent

UMR CNRS / URCA 7369 – « Extracellular Matrix and Cell Dynamics » (MEDyC)
Team 2 « Matrix Aging and Vascular Remodeling »
UFR Sciences Exactes et Naturelles – Campus Moulin de la Housse
51687 REIMS Cedex 2
Phone: +33 (0)3 26 91 89 39 | | Fax: +33 (0)3 26 91 83 66
Email address: laurent.duca@univ-reims.fr

Parcours professionnel

Laurent Duca is Associate Professor at the University of Reims Champagne-Ardenne where he leads with Pr. Philippe Gillery a team dealing with Matrix Aging and Vascular Remodeling. This team belongs to the CNRS associated research unit UMR CNRS/URCA 7369 MEDyC, a major lab in France specialized in cell/extracellular matrix interactions studies in pathophysiological contexts such as aging and cancer. He is interested in the molecular mechanisms leading to vascular elastolysis and in the role played by elastin-derived peptides (EDP) in the development of vascular diseases such as atherosclerosis. Using integrative technologies from Biochemistry, Cell Biology, Imaging, in vivo murine models (WT or transgenic) and in silico approaches (developed in collaboration with Pr. Manuel Dauchez’s group, UMR CNRS 7369), he extensively studied the signaling pathways and the operating mechanism of the Elastin Receptor Complex (ERC). The data gathered allowed him to propose a new pharmacology targeting the ERC and permitting to limit the deleterious involvement of elastin peptides in pathological vascular remodeling. His team also develops thematic dealing with the role of EDP in diabetes outcome, regulation of thrombosis and new molecular therapeutic approaches targeting the ERC. Moreover, a research axis on non enzymatic post-translational modifications of extracellular matrix proteins (carbamylation, glycoxydation) and their implication during aging is also developed (leading by Pr. Philippe Gillery).
Laurent Duca obtained his PhD in Biochemistry and Molecular Biology in 2004 at the University of Reims Champagne-Ardenne. He then performed a post-doctoral training in Toulouse at INSERM and Pierre Fabre laboratories where he studied molecular genetics approaches to modulate pathological cutaneous and corneal wound healing. He then joined his current lab as Associate Professor. He has published more than 40 articles in internationally renowned journals with a primary focus on elastin, elastin-derived peptides and the Elastin Receptor Complex.


Conseiller

JACOB Marie-Paule

Inserm U1148 – LVTS
Hôpital Bichat-Claude Bernard
46 rue Henri Huchard
75877 PARIS Cedex 18
Phone: +33 (0)1 40 25 86 17 | | Fax: +33 (0)1 40 25 86 02
Email address: marie-paule.jacob-lenet@inserm.fr

Parcours professionnel


Conseiller

LEHMANN Maxime

“Tumor signaling-Integrin and cancer” team
Laboratory of Biophotonics and Pharmacology, CNRS UMR7213
University of Strasbourg
Faculty of Pharmacy, 74 route du Rhin
67401 ILLKIRCH
Phone: +33 (0)3 68 85 41 92 | | Fax: +33 (0)3 68 85 43 13
Email address: maxime.lehmann@unistra.fr

Parcours professionnel

Maxime Lehmann is Professor in Cell Biology at the Faculty of Pharmacy of the Strasbourg University. Maxime was appointed Professor in 2011 when in joined the group “Integrin and cancer” from the Laboratory of Biophotonics and Pharmacology. This group is interested on the role of integrins, a major class of extracellular matrix receptors in cancer resistance to therapies. Maxime obtained a PhD in Biochemistry and Microbiology in 1994 in Marseille. During his PhD, he developed one of the first function-blocking antidody against the αv integrin family. Thereafter, he pursued a 3-years post-doc at the department of Pathology of Montreal University in Pr Lisa McKerracher’s team where he worked on the role of laminin and integrin in neuronal growth cone motility. He discovered the central role of Rho GTPases in axonal regrowth inhibition after CNS injury. Thereafter, he joined Aix-Marseille University as an assistant professor (Center for Research in Oncology and Oncopharmacology) where he worked on the role of integrins in colon carcinoma cell invasion. He also established partnerships with private companies to study epidermal wound healing. Currently, Maxime worked on the role of the integrin fibronectin receptor on glioblastoma cell invasion and resistance to targeted therapies. Maxime has published 40 papers in international renowned journals and is authors of two patents.


Représentante étudiant invitée

MONTMASSON Marine

Cell / microenvironment cross-talk and tissue repair lab
Biologie Tissulaire et Ingénierie Thérapeutique Department
UMR 5305 – CNRS/UCB Lyon 1- SFR BioSciences Gerland-Lyon Sud
7 passage du Vercors – 69367 Lyon Cedex 07, France
Phone: +33 (0)4 72 72 26 30 | | Fax: +33 (0)4 72 72 26 02
Email address: marine.montmasson@ibcp.fr

Parcours professionnel

Marine Montmasson is a 3rd year PhD student at the Tissue Biology and Therapeutic Engineering Department of the Institute of Protein Biology and Chemistry in Lyon. She joined the Cell Microenvironment Crosstalk and Tissue Repair lab headed by Dr Patricia Rousselle in 2014 in the context of her master training period. This team is interested in studying the behaviour of keratinocytes during the wound healing reepithelialisation phase and their interaction with extracellular matrix components. Consequently, her Ph.D. project focuses on the syndecan-1 receptor and its implication in the biology of specific adhesion structures, called podosomes.
After two years of competitive entrance examination to pharmacy school, Marine pursued a bachelor’s degree in Biology and Chemistry at the Joseph Fourier University of Grenoble and at the University of Montreal. Then, she performed a master’s degree entitled “Health and Drug Engineering” between 2013 and 2015, and started her PhD program in October 2015 under Dr Patricia Rousselle supervision. Marine was invited as a student representative at the SFBMEc board since March 2017. She presents the viewpoints of students in SFBMEc board meetings and informs students about SFBMEc board activities and decisions. She is available for all student questions.


Conseiller

OREND Gertraud

INSERM U1109, ImmunoRhumatologie Moléculaire (IRM)
HOPITAL CIVIL – Institut d’Hématologie et d’Immunologie
1, Place de l’Hôpital
67091 STRASBOURG, France
Phone: +33 (0)3 68 85 39 96 | | Secretary: +33 (0)3 68 85 40 11
Email address: gertraud.orend@inserm.fr
Website: www.u1109.inserm.fr

Parcours professionnel

Gertraud Orend had studied Genetics, Biochemistry, Pharmacology and Organic Chemistry in Cologne, Germany, where she did her PhD in the laboratory of Walter Doerfler on epigenetic modifications arising from insertional mutagenesis in Adenovirus type 12-induced hamster tumors. Her observations contributed to the understanding of de novo methylation across the genome, a mechanism that plays an important role in cancer. After obtaining her PhD degree, G. Orend joined the laboratory of Erkki Ruoslahti as postdoctoral fellow at the Burnham Institute in La Jolla, CA, USA where she got interested in the question how cell adhesion regulates cell cycle progression in normal cells and moreover, how this anchorage-dependence is subverted in tumor cells. Then she joined the laboratory of Ruth Chiquet-Ehrismann at the Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland, where she investigated signal transduction pathways that are initiated by the interaction of cells with the extracellular matrix molecules fibronectin and tenascin-C, two molecules that are highly expressed in cancer tissue. Then she directed a group at the University of Basel, Switzerland where she continued to work on signal transduction pathways that are induced by cell adhesion to tenascin-C. In 2008 she became lab head of a team at INSERM, U682 and U1109 (MN3T, The Microenvironmental Niche in Tumorigenesis and Targeted Therapy) in Strasbourg. She took tenascin-C research to a new level by developing mouse models with defined expression of tenascin-C. Currently, she is group leader in the Institute ImmunoRheumatologie Moléculaire (IRM) in Strasbourg. Her work is focussed on the understanding of the roles of tenascin-C in the tumor microenvironment promoting angiogenesis and metastasis and, shaping tumor immunity.


Conseiller

PAGNON-MINOT Aurélie

Société NOVOTEC
11 rue Edison
69500 BRON
Phone: +33 (0)4 78 61 46 31 | | Fax: +33 (0)4 78 61 46 32
Email address: apagnon@novotec-labs.com
Website: novotec-labs.com

Parcours professionnel

Aurélie Pagnon obtained a doctorate in Cellular and Molecular Biology in 2007. She began a PhD program with Dr. Florence Ruggiero at the Institute of Protein Biology and Chemistry of Lyon where she worked on collagens and their role in the development. After her thesis, she became Project Manager at Organogenesis Inc. (Canton, Mass., USA) where she performed in vitro studies to characterize a new generation of skin engineered products. She studied the biocompatibility, the integration and the biodegradability of biomaterials or of reconstructed skins by histology, immunohistochemistry, in situ hybridization and electron microscopy.
In 2010, she joined the NOVOTEC Society where she became R&D and Expertise’s Manager. Established at Bron (69) inside the activity zone of « Parc du Chêne », Novotec is situated near big scientific poles of the region of Lyon. Founded in 1997 by researchers of the Institut Pasteur of Lyon, Novotec is specialist in production and distribution of specific antibodies against the extracellular matrix macromolecules (collagens, elastin, fibronectin, laminin…). The improved knowledge of histological and immunohistochemical methods makes Novotec an expert in the tissue characterization. As a service provider, Novotec offers its expertise to the industrialists and the private or academic research laboratories (biotechnologies, pharmaceutics, bio-diagnosis, food processing industry, cosmetics, veterinary, tissue engineering…). Novotec also develops research programs on cutaneous and cartilage tissue engineering, in collaboration with French and foreign companies.


Conseiller

REYNAUD Caroline

INSERM U1033
Site Laennec
Equipe n°2 : Génomique fonctionnelle et traitements des métastases osseuses
7-11 rue Guillaume Paradin
69372 LYON Cedex 08
Phone: +33 (0)4 78 78 57 38
Email address: caroline.reynaud@inserm.fr

Parcours professionnel


Président d’honneur

BOREL Jacques-Paul

66 rue des Mathurins
75008 PARIS
Phone: +33 (0)1 42 65 19 86
Email address: jacques.borel4@wanadoo.fr

Parcours professionnel


Président d’honneur

LEGRAND Yves

INSERM U353
Hôpital St Louis
1 avenue Claude Vellefaux
75475 PARIS Cedex 10
Email address: yvlegrand@hotmail.com

Parcours professionnel


Présidente d’honneur

RICARD-BLUM Sylvie

ICBMS
UMR 5246 CNRS/Université Lyon 1
43 Boulevard du 11 Novembre
69622 VILLEURBANNE Cedex
Phone: +33 (0)4 72 44 82 32
Email address: sylvie.ricard-blum@univ-lyon1.fr

Parcours professionnel


Président d’honneur

ROBERT Ladislas

Décédé le 6 janvier 2018 dans sa 94ème année.


Dernière mise à jour : 09/02/2018.