Présidente (bureau)

ROUSSELLE Patricia

Cell / microenvironment cross-talk and tissue repair lab
Biologie Tissulaire et Ingénierie Thérapeutique Department
UMR 5305 – CNRS/UCB Lyon 1- SFR BioSciences Gerland-Lyon Sud
7 passage du Vercors – 69367 Lyon Cedex 07, France
Phone: 33 (0)4 72 72 26 39 | | Fax: 33 (0)4 72 72 26 02
Email address : patricia.rousselle@ibcp.fr
Website: http://www.ibcp.fr/lbti/-Environnement-Matriciel-Reparation-

Parcours professionnel

Patricia Rousselle is research director at CNRS in France where she leads a lab in the Tissue Biology and Therapeutic Engineering Department of the Institute of Protein Biology and Chemistry in Lyon. This department is one of the major centres in France specialising in the extracellular matrix and tissue repair field of research. Developing both biochemical and cell biology approaches, her group is interested in analysing the behaviour of keratinocytes during the reepithelialisation phase of wound repair and their interaction with extracellular matrix components. Besides, she develops translational research through collaborations with clinicians of the Lyon Burn Centre and industrial partners. Patricia is the present president of the French Matrix Society and is also a board member of the European Tissue Repair Society. Patricia obtained a doctorate in Pharmacy in 1988 and pursued a four-year residency in clinical biology at Lyon Hospitals, where she also gained an MSc in Molecular and Cellular Biology in 1990. Being interested in adhesion mechanisms of the epidermis, she started a PhD program with Prof Bob Burgeson at the Shriners Hospital For Crippled Children in Portland, USA, where she discovered the important dermal epidermal junction protein laminin 332. She thereafter joined the Cutaneous Biology Research Center in Boston, USA, to work on basement membrane biology, before she joined CNRS to set up her own group in 1995. Patricia Rousselle has published more than 90 articles on extracellular matrix proteins with a focus on laminins and proteoglycans, in internationally renowned journals. Dr. Rousselle’s special research interests include the role of basement membrane components and cell receptors, such as syndecans, in epithelial homeostasis and repair.

Secrétaire général (bureau)

EMONARD Hervé

UMR CNRS/URCA 7369 MEDyC
Responsable de l’équipe « Protéolyse et Cancer » – Laboratoire « Signalisation et Récepteurs Matriciels »
UFR Sciences Exactes et Naturelles – Bât. 18 RDC, bureau BR 21
Campus du Moulin de la Housse, BP 1039 – Chemin des Rouliers – 51687 REIMS Cedex 2
Tel: +33 (0)3 26 91 83 61 – Fax: +33 (0)3 26 91 83 66
Email address: herve.emonard@univ-reims.fr

Parcours professionnel

Hervé Emonard is associate scientist at CNRS in France where he leads the Proteolysis and Cancer Team of the UMR 7369 CNRS/URCA in Reims. Our unit is the leader in France for investigating the cytokine-like effects of degradation products, the matrikines, from two major components of the extracellular matrix, collagen and elastin. These matrikines are essentially studied in tumoral and vascular pathologies. Hervé is the present secretary of the French Extracellular Matrix Society.
Hervé obtained his PhD in 1984 at Lyon. A two-year post-doctoral fellowship in the laboratory of Profs Charles M. Lapière and Jean-Michel Foidart (University of Liege, Belgium) allowed him to familiarize himself with a family of proteolytic enzymes degrading extracellular matrix, the matrix metalloproteinases, MMPs. He joined CNRS in 1986 to study the extracellular matrix breakdown during hepatic fibrosis in Lyon. Then he moved to Reims in 1995, in the CNRS unit of Prof. François-Xavier Maquart to set up a group studying mechanisms of MMP inhibition with Prof. William Hornebeck. Hervé developped a strong collaboration with Prof. Pierre J. Courtoy (de Duve Institute, UCL, Brussels, Belgium) to understand the regulation of MMP extracellular levels by LRP-1-mediated endocytosis. Hervé Emonard has published more than 70 articles on the regulation of MMP activities, with a focus on MMP-2 and LRP-1.

Trésorière (bureau)

THERET Nathalie

Dynamique du Microenvironnement et Cancer
IRSET, Institut de Recherche en Santé, Environnement et Travail
INSERM U1085
2 avenue du Professeur Léon Bernard – 35043 Rennes Cédex
Tel: +33 (0)223 23 48 11
Email address: nathalie.theret@univ‐rennes1.fr

Parcours professionnel

Nathalie Théret is research Director at INSERM in France where she heads a research team at the Research Institute in Health, Environment and work (IRSET) supported by INSERM and University of Rennes 1. IRSET’s mission is to study biological processes and environmental factors that influence human health. Using multi-scale approaches combining molecular and cellular biology, biophysical and computational methods, her group is interested in studying extracellular matrix (ECM) remodeling in chronic liver diseases. Studies focus on the role of disintegrins and metalloproteases (ADAM) on TGF‐β signaling, the effects of ECM stiffness on hepatocyte functionality and the identification of a structure‐based signature for liver fibrosis evaluation by multiphotonic microscopy. Nathalie is the present treasury of the French Extracellular Matrix Society. Nathalie obtained her PhD in Pharmaceutic sciences in 1988 and pursued a two‐year post‐doctoral position in the laboratory of Pr Fruchart at Pasteur Institute (Lille) where she studied reverse cholesterol transport in cardiovascular diseases. She joined INSERM in 1991 and managed the «BioAvenir» Research Program in collaboration with Rhone Poulenc Roher Corporation focusing on the role of AI and AIV apolipoproteins. Next she moved in 1993 to the INSERM Unit directed by Pr Guillouzo (University of Rennes) and joined Dr B.Clement’s team to develop studies on extracellular matrix remodeling in liver cancers. To address the biological complexity of liver fibrosis and tumor progression, she sets up her own group in 2007 and develops systemic approaches for high-throughput data analysis and molecular modeling in collaboration with the Research Institute in Computational Research (INRIA). Nathalie Théret has published more than 70 articles and her research interests include ADAM proteins, TGFβ signaling and fibrosis.

Conseiller

BREZILLON Stéphane

UMR CNRS/URCA 7369 MEDyC
Laboratoire de Biochimie Médicale et Biologie Moléculaire
UFR Médecine
51 Rue Cognacq-Jay
51100 REIMS
Phone: +33 (0)3 26 91 37 34 | | Fax: +33 (0)3 26 91 80 55
Email address: stephane.brezillon@univ-reims.fr

Parcours professionnel

Stéphane Brézillon is associate scientist at CNRS in France where he leads with Prof. S. Dedieu the “ExtraCellular Matrix, Cancer and Therapeutic Targets” Team of the Research Unit MEDyC URCA/CNRS UMR 7369 in Reims.
Our unit is the leader in France for investigating the cytokine-like effects of degradation products, the matrikines, from major components of the extracellular matrix, collagen, elastin and proteoglycans. These matrikines are essentially studied in tumoral and vascular pathologies. Our team is focusing on LRP-1-mediated endocytosis and extracellular vesicles mediated cell communication between tumor cells, endothelial cells, and fibroblasts.
Stéphane Brézillon has obtained his Joint PhD in 1997 at Reims (Dr E. Puchelle (INSERM U514, University of Medicine, Reims, France) and at Hannover (Pr  B. Tümmler (Klinische Forschergruppe, Medizinische Hochschule Hannover, Germany). After a two-year post-doctoral fellowship in the laboratory of Prof G. Cramb (Saint Andrews, Scotland, UK), he became project leader in a biotechnology company, Euroscreen, Brussels, Belgium (1999-2004). Then, he moved to Reims in 2004 in the CNRS unit of Prof. François-Xavier Maquart to set up a group with Dr Y. Wegrowski studying the mechanisms of action of Lumican, a Small Leucine Rich Proteoglycan, able to inhibit melanoma progression. Using integrative technologies from Biochemistry, Cell Biology, Imaging, in vivo murine models (WT and lumican deleted mice) and in silico approaches (developed in collaboration with Pr. Manuel Dauchez’s group, UMR CNRS 7369), he extensively studied the signaling pathways, the mechanisms of action, and the modeling of Lumican with its receptors. He is developing a strong collaboration with Prof. Karamanos (University of Patras, Greece) and Prof. M. Gotte (University of Munster, Germany) and he belongs to the H2020 GLYCANC consortium.
Stéphane Brézillon has published more than 40 articles with a focus on lumican mechanism of action and its interaction with alpha2beta1 integrin and MMP-14.

Conseiller

CARREIRAS Franck

Université de Cergy Pontoise, ERRMECe, EA1391, Groupe MEC-uP
UFR Science et Technique
2 Av. Adolphe Chauvin
95302 CERGY-PONTOISE Cedex
Phone: +33 (0)1 34 25 66 75 | | Fax: +33 (0)1 34 25 66 94
Email address: franck.carreiras@u-cergy.fr

Parcours professionnel

Franck Carreiras is professor at the University of Cergy Pontoise and member of the ERRMECe lab.

In 1996, Franck obtained his PhD from the University of Caen in the unit of Biology and Innovative Therapies on the locally Aggressive Cancers, UMR INSERM 1199, BioTICLA of the F. Baclesse center. He then was a post-doc of the University of Aix-Marseille-II before being recruited at the University of Cergy Pontoise in 1998 as assistant professor. He obtained the habilitation degree in 2006 and got a Professor position in 2011.

He is now the leader of the group MEC-uP (Extracellular Matrix and Physiopathology) of the ERRMECe lab. Since the beginning, his general concern aims at positioning the matrix microenvironment in the center of his investigations. His recruitment at Cergy Pontoise allowed him to set up within the University a long-lasting theme concerning the influence of the matrix microenvironment on the tumoral dissemination. Since his nomination as leader of the MEC-uP group he continues this work on the tumoral microenvironment and the metastatic dissemination while diversifying his projects according to the knowledge of each members of his group (cellular ageing, tissue repair, surfaces functionalization). The characterization of the matrix microenvironment and its regulating impact on cellular activities stays at the center of his research. Franck Carreiras has published 40 articles, he directed 6 PhD and is also the director of the Master’s degree called BioC2M “Cellular and Molecular Biology of the Microenvironment”.


Conseiller

DUCA Laurent

UMR CNRS / URCA 7369 – « Extracellular Matrix and Cell Dynamics » (MEDyC)
Team 2 « Matrix Aging and Vascular Remodeling »
UFR Sciences Exactes et Naturelles – Campus Moulin de la Housse
51687 REIMS Cedex 2
Phone: +33 (0)3 26 91 89 39 | | Fax: +33 (0)3 26 91 83 66
Email address: laurent.duca@univ-reims.fr

Parcours professionnel

Laurent Duca is Associate Professor at the University of Reims Champagne-Ardenne where he leads with Pr. Philippe Gillery a team dealing with Matrix Aging and Vascular Remodeling. This team belongs to the CNRS associated research unit UMR CNRS/URCA 7369 MEDyC, a major lab in France specialized in cell/extracellular matrix interactions studies in pathophysiological contexts such as aging and cancer. He is interested in the molecular mechanisms leading to vascular elastolysis and in the role played by elastin-derived peptides (EDP) in the development of vascular diseases such as atherosclerosis. Using integrative technologies from Biochemistry, Cell Biology, Imaging, in vivo murine models (WT or transgenic) and in silico approaches (developed in collaboration with Pr. Manuel Dauchez’s group, UMR CNRS 7369), he extensively studied the signaling pathways and the operating mechanism of the Elastin Receptor Complex (ERC). The data gathered allowed him to propose a new pharmacology targeting the ERC and permitting to limit the deleterious involvement of elastin peptides in pathological vascular remodeling. His team also develops thematic dealing with the role of EDP in diabetes outcome, regulation of thrombosis and new molecular therapeutic approaches targeting the ERC. Moreover, a research axis on non enzymatic post-translational modifications of extracellular matrix proteins (carbamylation, glycoxydation) and their implication during aging is also developed (leading by Pr. Philippe Gillery).
Laurent Duca obtained his PhD in Biochemistry and Molecular Biology in 2004 at the University of Reims Champagne-Ardenne. He then performed a post-doctoral training in Toulouse at INSERM and Pierre Fabre laboratories where he studied molecular genetics approaches to modulate pathological cutaneous and corneal wound healing. He then joined his current lab as Associate Professor. He has published more than 40 articles in internationally renowned journals with a primary focus on elastin, elastin-derived peptides and the Elastin Receptor Complex.

 

Conseiller

LEHMANN Maxime

“Tumor signaling-Integrin and cancer” team
Laboratory of Biophotonics and Pharmacology, CNRS UMR7213
University of Strasbourg
Faculty of Pharmacy, 74 route du Rhin
67401 ILLKIRCH
Phone: +33 (0)3 68 85 41 92 | | Fax: +33 (0)3 68 85 43 13
Email address: maxime.lehmann@unistra.fr

Parcours professionnel

Maxime Lehmann is Professor in Cell Biology at the Faculty of Pharmacy of the Strasbourg University. Maxime was appointed Professor in 2011 when in joined the group “Integrin and cancer” from the Laboratory of Biophotonics and Pharmacology. This group is interested on the role of integrins, a major class of extracellular matrix receptors in cancer resistance to therapies. Maxime obtained a PhD in Biochemistry and Microbiology in 1994 in Marseille. During his PhD, he developed one of the first function-blocking antidody against the αv integrin family. Thereafter, he pursued a 3-years post-doc at the department of Pathology of Montreal University in Pr Lisa McKerracher’s team where he worked on the role of laminin and integrin in neuronal growth cone motility. He discovered the central role of Rho GTPases in axonal regrowth inhibition after CNS injury. Thereafter, he joined Aix-Marseille University as an assistant professor (Center for Research in Oncology and Oncopharmacology) where he worked on the role of integrins in colon carcinoma cell invasion. He also established partnerships with private companies to study epidermal wound healing. Currently, Maxime worked on the role of the integrin fibronectin receptor on glioblastoma cell invasion and resistance to targeted therapies. Maxime has published 40 papers in international renowned journals and is authors of two patents.

Conseiller

PAGNON-MINOT Aurélie

Société NOVOTEC
11 rue Edison
69500 BRON
Phone: +33 (0)4 78 61 46 31 | | Fax: +33 (0)4 78 61 46 32
Email address: apagnon@novotec-labs.com
Website: novotec-labs.com

Parcours professionnel

Aurélie Pagnon obtained a doctorate in Cellular and Molecular Biology in 2007. She began a PhD program with Dr. Florence Ruggiero at the Institute of Protein Biology and Chemistry of Lyon where she worked on collagens and their role in the development. After her thesis, she became Project Manager at Organogenesis Inc. (Canton, Mass., USA) where she performed in vitro studies to characterize a new generation of skin engineered products. She studied the biocompatibility, the integration and the biodegradability of biomaterials or of reconstructed skins by histology, immunohistochemistry, in situ hybridization and electron microscopy.
In 2010, she joined the NOVOTEC Society where she became R&D and Expertise’s Manager. Established at Bron (69) inside the activity zone of « Parc du Chêne », Novotec is situated near big scientific poles of the region of Lyon. Founded in 1997 by researchers of the Institut Pasteur of Lyon, Novotec is specialist in production and distribution of specific antibodies against the extracellular matrix macromolecules (collagens, elastin, fibronectin, laminin…). The improved knowledge of histological and immunohistochemical methods makes Novotec an expert in the tissue characterization. As a service provider, Novotec offers its expertise to the industrialists and the private or academic research laboratories (biotechnologies, pharmaceutics, bio-diagnosis, food processing industry, cosmetics, veterinary, tissue engineering…). Novotec also develops research programs on cutaneous and cartilage tissue engineering, in collaboration with French and foreign companies.

 

Conseiller

REYNAUD Caroline

INSERM U1033
Site Laennec
Equipe n°2 : Génomique fonctionnelle et traitements des métastases osseuses
7-11 rue Guillaume Paradin
69372 LYON Cedex 08
Phone: +33 (0)4 78 78 57 38
Email address: caroline.reynaud@inserm.fr

Parcours professionnel

Caroline Reynaud is senior scientist at CNRS in France where she leads the Lysyl oxidases and bone metastases group at the UMR 1033 INSERM/UCBL in Lyon. This unit is a major lab in France specialized in bone physiopathology. One of their objectives is to identify the underlying molecular mechanisms governing the nesting of tumor cells in the bone marrow and those that favor the formation of medullary micrometastases, the prelude required for bone metastasis formation. Additionally, they develop new biological markers of early relapse of cancer in bone will and test novel therapeutics in animal models of malignant bone diseases.

Caroline obtained her PhD in 2000 at the Ecole Normale Supérieure of Lyon. Her three-year post-doctoral fellowship on cell cycle in the laboratory of Prof Robert Margolis (IBS, Grenoble), led her to published important papers on the regulation of cell cycle checkpoints during tumor progression. She was recruited at the CNRS in 2003 in Pascal Sommer’s lab (IBCP, Lyon) to work on Lysyl oxidases and skin tumors. Then she moved to UMR1033 to study the role of Lysyl oxidases in the formation of the premetastatic niche into the bone marrow. Caroline has published more than 20 papers in renowned international journals.


Conseiller

RUGGIERO Florence

Institut de Génomique Fonctionnelle de Lyon, CNRS UMR 5242,
Ecole Normale Supérieure de Lyon
Université Claude Bernard Lyon 1,
46 allée d’Italie
69007 LYON
Phone: +33 (0)4 26 73 13 58
Email address: florence.ruggiero@ens-lyon.fr

Parcours professionnel


Représentante étudiant invitée

MONTMASSON Marine

Cell / microenvironment cross-talk and tissue repair lab
Biologie Tissulaire et Ingénierie Thérapeutique Department
UMR 5305 – CNRS/UCB Lyon 1- SFR BioSciences Gerland-Lyon Sud
7 passage du Vercors – 69367 Lyon Cedex 07, France
Phone: +33 (0)4 72 72 26 30 | | Fax: +33 (0)4 72 72 26 02
Email address: marine.montmasson@ibcp.fr

Parcours professionnel

Marine Montmasson is a 3rd year PhD student at the Tissue Biology and Therapeutic Engineering Department of the Institute of Protein Biology and Chemistry in Lyon. She joined the Cell Microenvironment Crosstalk and Tissue Repair lab headed by Dr Patricia Rousselle in 2014 in the context of her master training period. This team is interested in studying the behaviour of keratinocytes during the wound healing reepithelialisation phase and their interaction with extracellular matrix components. Consequently, her Ph.D. project focuses on the syndecan-1 receptor and its implication in the biology of specific adhesion structures, called podosomes.
After two years of competitive entrance examination to pharmacy school, Marine pursued a bachelor’s degree in Biology and Chemistry at the Joseph Fourier University of Grenoble and at the University of Montreal. Then, she performed a master’s degree entitled “Health and Drug Engineering” between 2013 and 2015, and started her PhD program in October 2015 under Dr Patricia Rousselle supervision. Marine was invited as a student representative at the SFBMEc board since March 2017. She presents the viewpoints of students in SFBMEc board meetings and informs students about SFBMEc board activities and decisions. She is available for all student questions.

Président d’honneur

BOREL Jacques-Paul

66 rue des Mathurins
75008 PARIS
Phone: +33 (0)1 42 65 19 86
Email address: jacques.borel4@wanadoo.fr

Parcours professionnel


Président d’honneur

LEGRAND Yves

INSERM U353
Hôpital St Louis
1 avenue Claude Vellefaux
75475 PARIS Cedex 10
Email address: yvlegrand@hotmail.com

Parcours professionnel


Présidente d’honneur

RICARD-BLUM Sylvie

ICBMS
UMR 5246 CNRS/Université Lyon 1
43 Boulevard du 11 Novembre
69622 VILLEURBANNE Cedex
Phone: +33 (0)4 72 44 82 32
Email address: sylvie.ricard-blum@univ-lyon1.fr

Parcours professionnel


Président d’honneur

ROBERT Ladislas

Décédé le 6 janvier 2018 dans sa 94ème année.


Dernière mise à jour : 10/10/2018.